PL Neuro Salon
Roadmapping the Neurotech Commons
About PL Neuro Salons
PL Neuro Salons are a series of small, invite-only meetings whose purpose is to accelerate the development of next generation technologies – like neural augmentation and human-like AI – in a manner that is targeted to benefit humanity. Toward this goal, PL Neuro Salons bring together a deliberately cross-disciplinary group of scientists, entrepreneurs, venture capitalists, and philanthropists with technical expertises across multiple disciplines of neuroscience and AI.
The PL Neuro Salon 2025: Roadmapping the Neurotech Commons
Human neural interface technology is at a turning point with significant investment in new devices and companies each year. As these devices enter clinical trials, large-scale human neural data collection is on the near-term horizon. This provides the opportunity to collect sufficient data to unlock insights about how brains compute that transcend biology and inform a substrate-independent “science of intelligence”. This, in turn, would qualitatively expand the capacities of next generation neurotechnologies, hastening their development, commercialization, and adoption.
Ensuring this outcome, however, requires an alignment of priorities across key stakeholders in the field such that the human neural data that is collected is useful not only for the clinical goals of current neural interface companies, but also for pushing forward intelligence science.
Goals
A major goal of the PL Neurotech Founders Retreat is to generate actionable 5 year roadmaps for each of the four session themes:
Unlocking $100B in venture capital
Smoothing the path to clinical revenue
Transitioning to consumer products
Preparing the public
For each of these sessions, our roadmaps should describe:
The state of neurotech today;
Our shared ideal state of the field in 5 years; and
Well-defined actionable steps that PL specially – and other actors more generally – can begin to take today to move the field towards the desired state.
These roadmaps can serve multiple functions. First, they inform and prioritize PL’s work and resource allocation. We want the companies PL is serving to feel confident that progress in the “neurotech commons” will occur without it needing to stem from their own work in isolation. This can allow companies to focus on their individual strengths. Second, these roadmaps may surface heretofore underexplored/unappreciated gaps that can rally actors (PL and others) towards solutions. Finally, one or more of these roadmaps can be published and disseminated such that key stakeholders like the public, patient groups, legislatures, regulators, payors, etc. are aware that the neurotech industry is thoughtfully tackling hard, shared problems whose solutions will allow the technology that is being developed to benefit more people faster.
While these roadmaps can and should address the needs of the neurotech field as a whole, it is also reasonable at times to narrow the scope of focus to the eight companies in attendance at the PL Neurotech Founders Retreat:
Blackrock
Echo
Integral
Motif
Paradromics
Precision
Science
Synchron
What to expect
This is a working meeting, not a conference.
The Salon will commence with a series of keynotes that frame the current state of neuroscience, neurotechnology, and AI. The core working sessions comprise short introductory framing remarks followed by breakout discussions focused on specific sub-topics. The goal is to clarify open problems, test assumptions, and surface areas of potential alignment. The rest of the schedule is designed to leave room for informal conversations and creative thinking.
There are no required presentations unless previously arranged.
Before the retreat
We ask all participants to read the Program and Attendee document in advance. It provides greater depth on the program and its scientific rationale as well as the intended outcomes of the retreat. It also lists the Salon attendees.
About
Tucked away on 160 acres of redwoods and rugged coastline, Alila Ventana Big Sur is an adults-only sanctuary designed for rest and renewal. The wild beauty of the Pacific meets thoughtful luxury here, with fireplaces, soaking tubs, and private decks inviting reflection. Hiking trails, wellness rituals, and locally sourced dining provide a deeper connection to nature. With sweeping ocean views and a quiet, restorative atmosphere, it is a place to pause, breathe, and rediscover balance.
Alila Ventana
Schedule
Here is a high-level view of the PL Neuro Salon schedule. Sessions are designed for collaborative, working discussions, not presentations, and the agenda balances structure with time for connection, exploration, and reflection.
Times and session topics are subject to minor adjustment.
What to Expect
Sessions are interactive, with short framing remarks and facilitated breakouts.
No formal slide presentations unless arranged in advance.
Comfortable clothing encouraged; bring layers for outdoor evening activities.
Evenings are lightly programmed and optional—time to connect or recharge.
FAQ
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Yes. Please arrange your own air travel to / from the surrounding airports. We suggest SFO, SJO, or Monterey.
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No. Protocol Labs will provide private suites at Alila Ventana for all participants from October 8–10, 2025.
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You’re welcome to arrive any time after 4:00 PM on Wednesday, October 8.. Formal programming begins in the early evening.
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Shift + Alt Events will be following up with those that requested a shuttle and direct you to the pickup spot based on your flight information.
If the times do not align or are outside of the schedule, please feel free to arrange your own transportation.
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Yes. Parking will be available for guests who drive in.
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Comfortable indoor/outdoor clothing
Layers for cool evenings
Walking shoes or trail-appropriate footwear
A notebook (optional)
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No formal dress code. Come as you’re comfortable.
The weather is generally mild and comfortable. Daytime highs are usually in the low 70s°F (around 22°C), with evenings cooling into the 50s°F (around 13°C). Conditions can shift quickly along the coast and in the mountains.
We recommend layers and walking shoes, especially for outdoor activities.
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Yes. All meals, drinks, and snacks are provided throughout the retreat.
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This is a closed, curated retreat with limited capacity. We kindly ask that you do not bring guests unless explicitly discussed with the organizers.
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There are no required talks or slides unless previously arranged. Sessions are designed to be conversational, with breakout discussions and optional evening participation.
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Yes, Wi-Fi will be available across the property. We encourage limited device use during sessions to stay present with the group.
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Shift + Alt Events are the Event Producers for this retreat, you can find out more about us here
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You can reach us any time at leila@shiftalt.events